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The
Avian Flu Blended Medicines Prevent and Treatment Guide
This
complete Guide will teach you all about Bird Flu prevention and treatments such
as Tamiflu and alternative cures. It includes info on:
Antivirals:
Know which antivirals to take, where to buy them and several dosage charts of
what to take before and after infection (Natural, Alternative and Conventional
Therapies that help your immune system)!
Flu Formula: Find out
what Natural Formula Dr. Pavel Nyvlt has had success with
Cytokines Storm:
In 1918 many died of an overactive immune system called a Cytokines Storm, find
out what this is and how to treat it!
New Drugs: Discover what
New Drug that may help against H5N1 and may be more effect than Tamiflu (this
drug will be in the HUMAN clinical trails stage early January 2006 held in the
United States). Not Tamiflu!
Understanding: What the Avian (Bird
or H5N1) Flu virus is and CURRENT Bird Flu events!
Avoid:
How to AVOID becoming infected
Preparation: How to PREPARE for
a possible Pandemic (checklists provided plus many links)
After Infection:
Know what to do if you become infected with the deadly flu virus
Aftermath
of Pandemic: Know what to expect after a Pandemic (Economy, Contacts and
how to SURVIVE)
Free Guides: Included links to survival guides,
first aid manual, bid flu information, other Avian Flu preparation guides and
plus so much more!
Free
Updates: Valuable information, plus be emailed with a FREE copy of the
Business and the community plan check lists when complete!
Read
the guide NOW... Are
you prepared for the bird flu pandemic?
The Bird Flu Survival Guide
is written by Stephen Jones, a prestigious Australian Biologist and is an easy
to read, clear and concise handbook on how to survive a bird flu outbreak. It
includes an detailed overview on quickly recognising bird flu symptons, preventative
measures, as well as commercial and alternative bird flu cures and treatments
that may one day save your and your families life. This is the only guide currently
available that will teach how to survive a bird flu outbreak. This is a great
reference to own, just in case. Be prepared!!!
Get
your copy of the Bird Flu Survival Guide NOW Bird
Flu and Tamiflu
Making Your Supply of Tamiflu Go Farther in an Emergency
by: Bradford Frank M.D., M.P.H., M.B.A. I
have discussed Tamiflu (oseltamivir) and Relenza (zanamivir) previously –
see Bird Flu: Tamiflu and Relenza for Prevention and Treatment in the Articles
section on our Web site, http://www.AvoidBirdFlu.com. This current article adds
important information about making your supply of Tamiflu go farther in an emergency
situation. First,
as I noted in my previous article, it is important to be aware of the fact that
the effectiveness of Tamiflu and Relenza has been studied against circulating
strains of human influenza (so called seasonal influenza), not against the bird
flu virus. In a study reported in the August 2005 issue of the Journal of Infectious
Diseases, Dr. Yen and others from St. Jude Children’s Research Hospital in
Memphis, Tennessee found that in animal experiments eight-day regimens of Tamiflu
were more effective than the suggested five-day regimen for treating infections
with the H5N1 bird-flu virus. The
authors concluded that a prolonged and higher-dose oseltamivir regimen may be
required for the most beneficial antiviral effect. This possibility was recently
underscored when two Vietnamese (one a 13 year old girl) died of bird flu—as
reported in a December 2005 issue of the New England Journal of Medicine—even
after receiving treatment within the required 48 hours after the start of infection
with standard doses of Tamiflu. Let’s
assume that you have one treatment course of Tamiflu (one 75 mg tablet taken twice
a day for five days, for a total of 10 pills), that you either acquired on your
own or that was given to you by your healthcare provider or by the government.
Unfortunately you are still not home free yet, so to speak. You now may face one
of two problems: Problem
# 1: If preliminary scientific studies indicating that a course of treatment of
bird flu using higher doses than those currently recommended by the FDA, for more
than the current recommended five days of treatment are correct—as indicated
by Dr. Yen’s research—you will need more that one dose pack. In fact,
the best treatment might mean taking two pills (150 mg) twice a day for eight
or even ten days. That would mean that you should have FOUR dose packs (40 pills)
for the treatment of one person, not just one! Problem
# 2: You have a dose pack—officially the amount need to treatment one person—but
there are two people who just became infected with bird flu in your family. If
you combine this problem with problem number one, you now actually need EIGHT
dose packs, not just two! What
can you do? There are two possible solutions: SOLUTION
# 1: Take PROBENECID, a medicine approved for the treatment of gout, along with
the Tamiflu. Probenecid interferes with the normal metabolism of Tamiflu, increasing
the blood level of Tamiflu and keeping it in circulation longer—effectively
doubling the amount of Tamiflu “exposure.” The precise dose is unclear.
Until more scientific information becomes available, in an emergency situation,
for otherwise healthy adults, I would recommend taking one 500 mg table twice
daily. Probenecid is generally very safe. Nevertheless, I have included detailed
information about it below. According
to information about probenecid from the National Library of Medicine’s and
the National Institutes of Health’s Web site Medline Plus (available at http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202480.html):
Probenecid
(proe-BEN-e-sid) is used in the treatment of chronic gout or gouty arthritis.
These conditions are caused by too much uric acid in the blood. The medicine works
by removing the extra uric acid from the body. Probenecid does not cure gout,
but after you have been taking it for a few months it will help prevent gout attacks.
This medicine will help prevent gout attacks only as long as you continue to take
it. Probenecid
is also used to prevent or treat other medical problems that may occur if too
much uric acid is present in the body. Probenecid
is sometimes used with certain kinds of antibiotics to make them more effective
in the treatment of infections. Probenecid
is available only with your doctor's prescription, in the following dosage form
(tablets): a.
Before Using This Medicine In
deciding to use a medicine, the risks of taking the medicine must be weighed against
the good it will do. This is a decision you and your doctor will make. For probenecid,
the following should be considered: Allergies—Tell
your doctor if you have ever had any unusual or allergic reaction to probenecid.
Also tell your health care professional if you are allergic to any other substances,
such as foods, preservatives, or dyes. Pregnancy—Probenecid
has not been shown to cause birth defects or other problems in humans. Breast-feeding—Probenecid
has not been reported to cause problems in nursing babies. Children—Probenecid
has been tested in children 2 to 14 years of age for use together with antibiotics.
It has not been shown to cause different side effects or problems than it does
in adults. Studies on the effects of probenecid in patients with gout have been
done only in adults. Gout is very rare in children. Older
adults—Many medicines have not been studied specifically in older people.
Therefore, it may not be known whether they work exactly the same way they do
in younger adults. There is no specific information comparing use of probenecid
in the elderly with use in other age groups. Other
medicines—Although certain medicines should not be used together at all,
in other cases two different medicines may be used together even if an interaction
might occur. In these cases, your doctor may want to change the dose, or other
precautions may be necessary. When you are taking probenecid, it is especially
important that your health care professional know if you are taking any of the
following: •
Antineoplastics (cancer medicine)—The chance of serious side effects may
be increased •
Aspirin or other salicylates—These medicines may keep probenecid from working
properly for treating gout, depending on the amount of aspirin or other salicylate
that you take and how often you take it •
Heparin—Probenecid may increase the effects of heparin, which increases the
chance of side effects •
Indomethacin (e.g., Indocin) •
Ketoprofen (e.g., Orudis) •
Methotrexate (e.g., Mexate)—Probenecid may increase the blood levels of these
medicines, which increases the chance of side effects •
Medicine for infection, including tuberculosis or virus infection—Probenecid
may increase the blood levels of many of these medicines. In some cases, this
is a desired effect and probenecid may be used to help the other medicine work
better. However, the chance of side effects is sometimes also increased •
Nitrofurantoin (e.g., Furadantin)—Probenecid may keep nitrofurantoin from
working properly •
Zidovudine (e.g., AZT, Retrovir)—Probenecid increases the blood level of
zidovudine and may allow lower doses of zidovudine to be used. However, the chance
of side effects is also increased Other
medical problems—The presence of other medical problems may affect the use
of probenecid. Make sure you tell your doctor if you have any other medical problems,
especially: •
Blood disease or •
Cancer being treated by antineoplastics (cancer medicine) or radiation (x-rays)
or •
Kidney disease or stones (or history of) or •
Stomach ulcer (history of)—The chance of side effects may be increased b.
Proper Use of This Medicine If probenecid upsets your stomach, it may be taken
with food. If this does not work, an antacid may be taken. If stomach upset (nausea,
vomiting, or loss of appetite) continues, check with your doctor. For
patients taking probenecid for gout: •
After you begin to take probenecid, gout attacks may continue to occur for a while.
However, if you take this medicine regularly as directed by your doctor, the attacks
will gradually become less frequent and less painful than before. After you have
been taking probenecid for several months, they may stop completely. •
This medicine will help prevent gout attacks but it will not relieve an attack
that has already started. Even if you take another medicine for gout attacks,
continue to take this medicine also. If you have any questions about this, check
with your doctor. For
patients taking probenecid for gout or to help remove uric acid from the body:
•
When you first begin taking probenecid, the amount of uric acid in the kidneys
is greatly increased. This may cause kidney stones or other kidney problems in
some people. To help prevent this, your doctor may want you to drink at least
10 to 12 full glasses (8 ounces each) of fluids each day, or to take another medicine
to make your urine less acid. It is important that you follow your doctor's instructions
very carefully. Dosing—
The
dose of probenecid will be different for different patients. Follow your doctor's
orders or the directions on the label. The following information includes only
the average doses of probenecid. If your dose is different, do not change it unless
your doctor tells you to do so. •
For treating gout or removing uric acid from the body: ?
Adults: 250 mg (one-half of a 500-mg tablet) two times a day for about one week,
then 500 mg (one tablet) two times a day for a few weeks. After this, the dose
will depend on the amount of uric acid in your blood or urine. Most people need
2, 3, or 4 tablets a day, but some people may need higher doses. ?
Children: It is not likely that probenecid will be needed to treat gout or to
remove uric acid from the body in children. If a child needs this medicine, however,
the dose would have to be determined by the doctor. •
For helping antibiotics work better: ?
Adults: The amount of probenecid will depend on the condition being treated. Sometimes,
only one dose of 2 tablets is needed. Other times, the dose will be 1 tablet four
times a day. ?
Children: The dose will have to be determined by the doctor. It depends on the
child's weight, as well as on the condition being treated. Older children and
teenagers may need the same amount as adults. Missed
dose— If
you are taking probenecid regularly and you miss a dose, take the missed dose
as soon as possible. However, if you do not remember until it is almost time for
the next dose, skip the missed dose and go back to your regular dosing schedule.
Do not double doses. Storage—
To store
this medicine: •
Keep out of the reach of children. •
Store away from heat and direct light. •
Do not store this medicine in the bathroom, near the kitchen sink, or in other
damp places. Heat or moisture may cause the medicine to break down. •
Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded
medicine is out of the reach of children. c.
Precautions While Using This Medicine •
If you will be taking probenecid for more than a few weeks, your doctor should
check your progress at regular visits. Before
you have any medical tests, tell the person in charge that you are taking this
medicine. The results of some tests may be affected by probenecid. For
diabetic patients: •
Probenecid may cause false test results with copper sulfate urine sugar tests
(Clinitest®), but not with glucose enzymatic urine sugar tests (Clinistix®).
If you have any questions about this, check with your health care professional.
For
patients taking probenecid for gout or to help remove uric acid from the body:
•
Taking aspirin or other salicylates may lessen the effects of probenecid. This
will depend on the dose of aspirin or other salicylate that you take, and on how
often you take it. Also, drinking too much alcohol may increase the amount of
uric acid in the blood and lessen the effects of this medicine. Therefore, do
not take aspirin or other salicylates or drink alcoholic beverages while taking
this medicine, unless you have first checked with your doctor. d.
Side Effects of This Medicine Along
with its needed effects, a medicine may cause some unwanted effects. Although
not all of these side effects may occur, if they do occur they may need medical
attention. The
following side effects may mean that you are having an allergic reaction to this
medicine. Check with your doctor immediately if any of the following side effects
occur: •
Rare Fast
or irregular breathing; puffiness or swellings of the eyelids or around the eyes;
shortness of breath, troubled breathing, tightness in chest, or wheezing; changes
in the skin color of the face occurring together with any of the other side effects
listed here; or skin rash, hives, or itching occurring together with any of the
other side effects listed here Also,
check with your doctor as soon as possible if any of the following side effects
occur: •
Less common Bloody
urine; difficult or painful urination ; lower back or side pain (especially if
severe or sharp); skin rash, hives, or itching (occurring without other signs
of an allergic reaction) •
Rare Cloudy
urine; cough or hoarseness; fast or irregular breathing; fever; pain in back and/or
ribs; sores, ulcers, or white spots on lips or in mouth; sore throat and fever
with or without chills; sudden decrease in the amount of urine; swelling of face,
fingers, feet, and/or lower legs; swollen and/or painful glands ; unusual bleeding
or bruising; unusual tiredness or weakness; yellow eyes or skin ; weight gain
Other
side effects may occur that usually do not need medical attention. These side
effects may go away during treatment as your body adjusts to the medicine. However,
check with your doctor if any of the following side effects continue or are bothersome:
•
More common Headache;
joint pain, redness, or swelling ; loss of appetite; nausea or vomiting (mild)
•
Less common Dizziness;
flushing or redness of face (occurring without any signs of an allergic reaction);
frequent urge to urinate; sore gums Other
side effects not listed above may also occur in some patients. If you notice any
other effects, check with your doctor. SOLUTION
# 2: Unless you are a divine follower of the late Mahatma Gandhi, who used to
drink his urine daily, this solution is not nearly as appealing as taking probenecid.
However, it apparently would be very effective. Dr. Grattan Woodson, a specialist
in internal medicine at the Druid Oaks Health Center in Decatur, Georgia, offers
the following advice for emergency treatment of bird flu:* This is an advanced,
potentially life-saving emergency strategy, that should only be done under medical
supervision—unless none is available. Tamiflu
Re-Administration Strategy: Tamiflu is excreted unchanged almost entirely in the
urine. If Tamiflu supplies are limited, as they most certainly will be [during
a bird-flu pandemic], consider giving the patient two Tamiflu tablets at the same
time, collect the patient’s urine and re-administer it to the patient via
naso-gastric (NG) tube or orally. If managed carefully, this approach means that
you can completely treat a patient with only 2 Tamiflu tablets [by re-administering
the patient’s urine daily for five to 10 days]. How and where to buy Tamiflu. *Woodson
G: Preparing for The Coming Influenza Pandemic. Fluwikie.com. Available at: http://fluwikie.com/annex/WoodsonMonograph.htm#_Toc116746508.
About
The Author
Bradford
Frank M.D., M.P.H., M.B.A.
Dr.
Bradford Frank graduated from the University of Colorado with a B.A. in chemistry
and his M.D. degree. He completed two residencies, one in family practice and
one in psychiatry. He is a clinical assistant professor at the University of Buffalo
School of Medicine and Biomedical Sciences, Buffalo, New York. He has a master’s
degree in public health (M.P.H.) from Yale (1992), where he studied infectious
diseases, and a master’s in business administration (M.B.A.) from Northwestern
University’s Kellogg School of Management (2003).
Dr.
Frank has expertise in the areas of business continuity and strategic planning,
emerging infectious diseases, severe acute respiratory syndrome (SARS), avian
influenza (bird flu), weapons of mass destruction, terrorism, epidemiology, various
public health issues, health and wellness, and wealth. He
is president of The Frank Group, a diverse group of businesses, and executive
director and host of The Health and Wealth Show, an Internet radio talk show (www.TheHealthandWealthShow.com),
which will be starting in February 2006. He
is the author of numerous scientific articles and several books. His latest article
is A Review of Antioxidants and Alzheimer’s Disease, published in the October-December
2005 issue of Annals of Clinical Psychiatry. He is the author of Bird Flu: Overview
and Economic Considerations - Special Report, and a series of DVDs about bird
flu. He is the author of a series of DVDs about the 2003 SARS (severe acute respiratory
syndrome) pandemic in Toronto, which includes in-depth on-camera interviews with
seven doctors involved in the outbreak, and which has direct relevance to the
coming bird-flu pandemic. His new book is Bird Flu: Expert Advice to Help You
and Your Family Stay Safe (see www.AvoidBirdFlu.com for details). Dr.
Frank is married and has three children. He lives in upper state New York where
he enjoys hiking, sailing, and skiing. He is a black belt in Tae Kwon Do. (For
further information visit http://www.BradFrankMD.com.)
Articles
of Interest
Review
of Informational Health products
Bird
Flu Pandemic
Travelling to an area
affected by the bird flu
Panick Attacks
- the Linden Method
Effective Dieting - loose
weight quickly
Asian Flu pandemic and Tamiflu
Birdflu
and Human Infection
Birdflu
Preperation
How and where to buy Tamiflu
Coping
with panic attacks
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